MMP26 antibody (C-Term)

Catalog No. ABIN2787275

Product Details anti-MMP26 Antibody

Target: MMP26 (Matrix Metallopeptidase 26 (MMP26))

Binding Specificity: C-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP26 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NLFLVATHEI GHSLGLQHSG NQSSIMYPTY WYHDPRTFQL SADDIQRIQH

Predicted Reactivity: Human: 100%, Rat: 83%

Characteristics: This is a rabbit polyclonal antibody against MMP26. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MMP26

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 261 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MMP26

Target: MMP26 (Matrix Metallopeptidase 26 (MMP26))

Alternative Name: MMP26 (MMP26 Products)

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein degrades type IV collagen, fibronectin, fibrinogen, casein, vitronectin, alpha 1-antitrypsin, alpha 2-macroglobulin, and insulin-like growth factor-binding protein 1, and activates MMP9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain.
Alias Symbols: MGC126590, MGC126592
Protein Interaction Partner: SERPINA1, IGFBP1, MMP9,
Protein Size: 261

Molecular Weight: 19 kDa

Gene ID: 56547

NCBI Accession: NM_021801, NP_068573

UniProt: Q9NRE1