PPP2R1B antibody (N-Term)

Catalog No. ABIN2787390

Product Details anti-PPP2R1B Antibody

Target: PPP2R1B (Protein Phosphatase 2, Regulatory Subunit A, beta (PPP2R1B))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Zebrafish (Danio rerio), Guinea Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R1B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EDVQLRLNSI KKLSTIALAL GVERTRSELL PFLTDTIYDE DEVLLALAEQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against PPP2R1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PPP2R1B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 667 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPP2R1B

Target: PPP2R1B (Protein Phosphatase 2, Regulatory Subunit A, beta (PPP2R1B))

Alternative Name: PPP2R1B (PPP2R1B Products)

Synonyms: 2410091N08Rik antibody, AI790395 antibody, PP2A-Abeta antibody, PR65B antibody, protein phosphatase 2, regulatory subunit A, beta antibody, protein phosphatase 2 scaffold subunit Abeta antibody, protein phosphatase 2 scaffold subunit A beta antibody, protein phosphatase 2 regulatory subunit A, beta S homeolog antibody, Ppp2r1b antibody, PPP2R1B antibody, ppp2r1b.S antibody

Background: This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric co
Alias Symbols: MGC26454, PR65B, PP2A-Abeta
Protein Interaction Partner: UBC, PPP2R1A, IKBKG, DNAAF5, ARPC1A, ARPC5, EGFR, FBXW4, STK24, POLA1, STK25, CFTR, PPP2R5D, PPP2R2A, PPP2CA, CAV1, SUMO2, RAB18, PARK7, RAB11A, RAB7A, PRDX2, STRN, STAT3, RALA, PPP2R5E, PPP2R5C, PRDX1, MCM3, HDAC1, FGFR1, EEF2, CDK4, CDK1, ANXA5, Sgol2,
Protein Size: 667

Molecular Weight: 73 kDa

Gene ID: 5519

NCBI Accession: NM_181699, NP_859050

UniProt: A8K8B0

Pathways: PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades