PCSK6 antibody (N-Term)
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- Target See all PCSK6 Antibodies
- PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))
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Binding Specificity
- N-Term
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Reactivity
- Human, Rat, Rabbit, Mouse, Cow, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PCSK6 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- NYDSYASYDV NGNDYDPSPR YDASNENKHG TRCAGEVAAS ANNSYCIVGI
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against PCSK6. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PCSK6
- Top Product
- Discover our top product PCSK6 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 975 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))
- Alternative Name
- PCSK6 (PCSK6 Products)
- Synonyms
- PACE4 antibody, PCSK6 antibody, SPC4 antibody, C86343 antibody, Pace4 antibody, Spc4 antibody, PACE4AIIa antibody, Xpace4 antibody, spc4 antibody, proprotein convertase subtilisin/kexin type 6 antibody, peptidase S8 antibody, proprotein convertase subtilisin/kexin type 6 L homeolog antibody, PCSK6 antibody, EAMY_RS27925 antibody, pcsk6 antibody, Pcsk6 antibody, pcsk6.L antibody
- Background
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PCSK6 is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. This gene is thought to play a role in tumor progression.The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: PACE4, SPC4
Protein Interaction Partner: env, UBC, CACNA1A, RCN3, FLG, PMCH, PCSK6,
Protein Size: 975 - Molecular Weight
- 91 kDa
- Gene ID
- 5046
- NCBI Accession
- NM_138320, NP_612193
- UniProt
- Q63415
- Pathways
- Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
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