TAF1C antibody (N-Term)

Catalog No. ABIN2787455

Product Details anti-TAF1C Antibody

Target: TAF1C (TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kDa (TAF1C))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Dog, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAF1C antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MDFPSSLRPA LFLTGPLGLS DVPDLSFMCS WRDALTLPEA QPQNSENGAL

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 77%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against TAF1C. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TAF1C

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 869 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TAF1C

Target: TAF1C (TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kDa (TAF1C))

Alternative Name: TAF1C (TAF1C Products)

Synonyms: TAF1C antibody, Tafi95 antibody, mTAFI95 antibody, MGC:39976 antibody, SL1 antibody, TAFI110 antibody, TAFI95 antibody, TATA-box binding protein associated factor, RNA polymerase I subunit C antibody, TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa antibody, TATA-box binding protein associated factor, RNA polymerase I, C antibody, TATA-box binding protein associated factor, RNA polymerase 1 subunit C antibody, TAF1C antibody, Taf1c antibody

Background: Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. TAF1C is the largest SL1-specific TAF. Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.
Alias Symbols: MGC:39976, SL1, TAFI110, TAFI95
Protein Interaction Partner: UBC, Tbp, Taf1b, Taf1a, UFD1L, TTR, TK1, SMN1, H2AFX, TAF12, TAF1D, POLR1E, RRN3, TRIM24, TP53, UBTF, CD3EAP, MYC,
Protein Size: 869

Molecular Weight: 95 kDa

Gene ID: 9013

NCBI Accession: NM_005679, NP_005670

UniProt: Q15572