Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

PSMD4/ASF antibody (N-Term)

Psmd4 Reactivity: Human, Mouse, Rat, Cow, Sheep, Rabbit, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Saccharomyces cerevisiae WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2787532
  • Target See all PSMD4/ASF (Psmd4) Antibodies
    PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))
    Binding Specificity
    • 18
    • 14
    • 7
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 64
    • 19
    • 18
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    Human, Mouse, Rat, Cow, Sheep, Rabbit, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Saccharomyces cerevisiae
    Host
    • 58
    • 6
    • 1
    • 1
    Rabbit
    Clonality
    • 60
    • 6
    Polyclonal
    Conjugate
    • 36
    • 6
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSMD4/ASF antibody is un-conjugated
    Application
    • 56
    • 38
    • 21
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    VLESTMVCVD NSEYMRNGDF LPTRLQAQQD AVNIVCHSKT RSNPENNVGL
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 92%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against PSMD4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human PSMD4
    Top Product
    Discover our top product Psmd4 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 377 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ghi, Di Brisco, Dallorto, Osella, Orsetti: "Age-related modifications of egr1 expression and ubiquitin-proteasome components in pet dog hippocampus." in: Mechanisms of ageing and development, Vol. 130, Issue 5, pp. 320-7, (2009) (PubMed).

  • Target
    PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))
    Alternative Name
    PSMD4 (Psmd4 Products)
    Synonyms
    af-1 antibody, mcb1 antibody, pub-r5 antibody, rpn10 antibody, PSMD4 antibody, DDBDRAFT_0202512 antibody, DDBDRAFT_0232981 antibody, DDB_0202512 antibody, DDB_0232981 antibody, AF antibody, AF-1 antibody, ASF antibody, MCB1 antibody, Rpn10 antibody, S5A antibody, pUB-R5 antibody, xrpn10c antibody, Af1 antibody, Mcb1 antibody, angiocidin antibody, im:6912672 antibody, psmd4 antibody, wu:fc68c04 antibody, zgc:110247 antibody, proteasome 26S subunit, non-ATPase 4 antibody, 26S proteasome non-ATPase regulatory subunit 4 antibody, 26s proteasome non-atpase regulatory subunit 4 (26s proteasomeregulatory subunit s5a) antibody, proteasome 26S subunit, non-ATPase 4 L homeolog antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 antibody, proteasome 26S subunit, non-ATPase 4b antibody, psmd4 antibody, PSMD4 antibody, LOC100194679 antibody, psmD4 antibody, LOC100283637 antibody, Smp_000740.1 antibody, psmd4.L antibody, Psmd4 antibody, psmd4b antibody
    Background
    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD4 encodes one of the non-ATPase subunits of the 19S regulator lid. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Pseudogenes have been identified on chromosomes 10 and 21. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: AF, AF-1, ASF, MCB1, Rpn10, S5A, pUB-R5
    Protein Interaction Partner: UBC, cdc20, XPC, SPRTN, PSMD14, MDM2, PSMC2, PSMA1, ADRM1, UBQLN1, TXNL1, PSMD3, PSMD2, PSMD1, PSMC6, PSMC4, PSMC1, UCHL5, RPS12, PSMD8, UBQLN4, VCP, GJA1, DIO2, SCHIP1, FBXO6, PARK2, UL76, FBXO25, LOC100044627, Gm4705, LOC677113, Rps6-ps4, Rpl34-ps1, Rpl
    Protein Size: 377
    Molecular Weight
    41 kDa
    Gene ID
    5710
    NCBI Accession
    NM_002810, NP_002801
    UniProt
    P55036
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
You are here:
Support