BPGM antibody (Middle Region)

Catalog No. ABIN2787596

Product Details anti-BPGM Antibody

Target: BPGM (2,3-bisphosphoglycerate Mutase (BPGM))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BPGM antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EQVRLWRRSY NVTPPPIEES HPYYQEIYND RRYKVCDVPL DQLPRSESLK

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 93%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against BPGM. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BPGM

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 259 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BPGM

Target: BPGM (2,3-bisphosphoglycerate Mutase (BPGM))

Alternative Name: BPGM (BPGM Products)

Synonyms: DPGM antibody, AI323730 antibody, AL022789 antibody, C86192 antibody, Ab2-098 antibody, zgc:92230 antibody, Bisphosphoglycerate mutase antibody, bisphosphoglycerate mutase antibody, 2,3-bisphosphoglycerate mutase antibody, bisphosphoglycerate mutase S homeolog antibody, pmge antibody, BPGM antibody, Bpgm antibody, bpgm antibody, bpgm.S antibody

Background: BPGM belongs to the phosphoglycerate mutase family, BPG-dependent PGAM subfamily. It plays a major role in regulating hemoglobin oxygen affinity as a consequence of controlling 2,3-BPG concentration. It can also catalyze the reaction of EC 5.4.2.1 (mutase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.
Alias Symbols: DPGM
Protein Interaction Partner: UBC, EHD2, ATF6, NEK3, EGR2, CEL, ATP4B, SPEN, GRB2, AKT1, GAPDH,
Protein Size: 259

Molecular Weight: 28 kDa

Gene ID: 669

NCBI Accession: NM_001724, NP_001715

UniProt: P07738