PDS5B antibody (Middle Region)
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- Target See all PDS5B Antibodies
- PDS5B (PDS5, Regulator of Cohesion Maintenance, Homolog B (PDS5B))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Pig, Rabbit, Zebrafish (Danio rerio), Cow, Dog, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PDS5B antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- DEQQWPEEKR LKEDILENED EQNSPPKKGK RGRPPKPLGG GTPKEEPTMK
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
- Characteristics
- This is a rabbit polyclonal antibody against PDS5B. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PDS5B
- Top Product
- Discover our top product PDS5B Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1447 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PDS5B (PDS5, Regulator of Cohesion Maintenance, Homolog B (PDS5B))
- Alternative Name
- PDS5B (PDS5B Products)
- Synonyms
- APRIN antibody, AS3 antibody, CG008 antibody, Aprin antibody, as3 antibody, aprin antibody, AI646570 antibody, AW212954 antibody, mKIAA0979 antibody, pds5b antibody, PDS5 cohesin associated factor B antibody, PDS5 cohesin associated factor B L homeolog antibody, PDS5B antibody, Pds5b antibody, pds5b antibody, pds5b.L antibody
- Background
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PDS5B plays a role in androgen-induced proliferative arrest in prostate cells. It is required for maintenance of sister chromatid cohesion during mitosis. Defects in PDS5B may be the cause of some cancers including esophageal cancer.
Alias Symbols: APRIN, AS3, CG008, FLJ23236, KIAA0979, RP1-267P19.1
Protein Interaction Partner: UBC, EED, RNF2, CDCA5, LAMP2, APP, NSMCE2, SIRT7, RAD21, STAG2, STAG1, SMC3, SMC1A, SUMO1, WAPAL, WFDC5, PDS5A, tat,
Protein Size: 1447 - Molecular Weight
- 159 kDa
- Gene ID
- 23047
- NCBI Accession
- NM_015032, NP_055847
- UniProt
- Q9NTI5
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