DLD antibody (Dihydrolipoamide Dehydrogenase) (Middle Region)

Details for Product anti-DLD Antibody No. ABIN2787688, Supplier: Log in to see
Antigen
  • DLD
  • DDBDRAFT_0183800
  • DDBDRAFT_0216232
  • DDB_0183800
  • DDB_0216232
  • DLDH
  • DLDD
  • E3
  • GCSL
  • LAD
  • PHE3
  • wu:fb24b05
  • AI315664
  • AI746344
  • 4733401P21Rik
  • D8Bwg1320e
  • dihydrolipoamide dehydrogenase
  • dihydrolipoyl dehydrogenase
  • lactate dehydrogenase D
  • DLD
  • AT4G16155
  • CND05840
  • bfmBC
  • GCSL
  • LACBIDRAFT_182385
  • UREG_06178
  • lpd
  • Tagg_0410
  • Arnit_2606
  • Mesil_1945
  • Trad_2118
  • Deba_2198
  • Deba_2981
  • Toce_0808
  • Toce_1429
  • Toce_2027
  • Acear_0640
  • Fbal_0372
  • Ilyop_1890
  • Lbys_2718
  • Lbys_3490
  • Ftrac_1733
  • Ocepr_1753
  • Intca_2017
  • Deima_0504
  • dldh
  • Dld
  • Ldhd
Alternatives
anti-Pig (Porcine) DLD antibody for ELISA
Epitope
Middle Region
17
7
5
5
5
4
2
2
2
2
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Yeast, Zebrafish
96
33
25
25
7
6
2
2
2
1
Host
Rabbit
73
57
Clonality
Polyclonal
Conjugate
This DLD antibody is un-conjugated
9
5
2
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
122
74
51
37
35
25
21
12
5
4
4
2
1
1
Options
Supplier
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human DLD
Blocking Peptide Blocking peptide for this product available: ABIN975823
Sequence AGEMVNEAAL ALEYGASCED IARVCHAHPT LSEAFREANL AASFGKSINF
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Yeast: 86%, Zebrafish: 93%
Characteristics This is a rabbit polyclonal antibody against DLD. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name DLD (DLD Antibody Abstract)
Background DLD is the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DLDH, E3, GCSL, LAD, PHE3
Protein Interaction Partner: HUWE1, FUS, UBC, SUMO1, NEDD8, MDM2, ASB15, PEPD, LDHA, CKB, ASS1, CNDP2, TNFAIP8, DPP3, RPL23, FN1, ATF2, MRPL11, UBAP2, MRPL37, MRPL13, MRPL42, GGH, UQCRC2, UQCRC1, MRPL23, NONO, NDUFB5, NDUFA9, ETFB, DLAT, DBT, AK2, SIRT7, SLC2A4, PSMD4, OGDH, DLD, PDH
Protein Size: 509
Molecular Weight 56 kDa
Gene ID 1738
NCBI Accession NM_000108, NP_000099
UniProt B2R5X0
Pathways Ribonucleoside Biosynthetic Process, Cell RedoxHomeostasis
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 509 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Dihydrolipoamide Dehydrogenase (DLD) (Middle Region) antibody (ABIN2787688) WB Suggested Anti-DLD Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1...
Western Blotting (WB) image for anti-Dihydrolipoamide Dehydrogenase (DLD) (Middle Region) antibody (ABIN2787688) anti-Dihydrolipoamide Dehydrogenase (DLD) (Middle Region) antibody (Image 2)
Product cited in: Ayanniyi, Raji, Adegoke: "Prevalence of asymptomatic sacroiliac joint dysfunction and its association with leg length discrepancies in male students in selected junior secondary schools in Ibadan." in: African journal of medicine and medical sciences, Vol. 37, Issue 1, pp. 37-42, 2008 (PubMed).

Background publications Wang, Wang, Li, Chen, Liu, Chen, Chou, Liu: "The role of amino acids T148 and R281 in human dihydrolipoamide dehydrogenase." in: Journal of biomedical science, Vol. 15, Issue 1, pp. 37-46, 2007 (PubMed).

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