ERLIN2 antibody (Middle Region)

Catalog No. ABIN2787692

Product Details anti-ERLIN2 Antibody

Target: ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERLIN2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ASNSKIYFGK DIPNMFMDSA GSVSKQFEGL ADKLSFGLED EPLETATKEN

Predicted Reactivity: Human: 100%, Mouse: 86%, Pig: 79%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ERLIN2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ERLIN2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 339 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ERLIN2 antibody (ABIN2787692)

Zhang, Yao, Yu, Ni, Zhang, Wang, Lai: "Effects of 1.8 GHz radiofrequency radiation on protein expression in human lens epithelial cells." in: Human & experimental toxicology, Vol. 32, Issue 8, pp. 797-806, (2013) (PubMed).

Target Details for ERLIN2

Target: ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))

Alternative Name: ERLIN2 (ERLIN2 Products)

Synonyms: C8orf2 antibody, Erlin-2 antibody, NET32 antibody, SPFH2 antibody, SPG18 antibody, BC036333 antibody, C87251 antibody, Spfh2 antibody, Erlin-2-B antibody, erlin1 antibody, spfh1 antibody, spfh2 antibody, spfh2-B antibody, RGD1309010 antibody, SPFH domain-containing protein 2-A antibody, erlin2 antibody, erlin2-a antibody, erlin2-b antibody, spfh2-A antibody, ER lipid raft associated 2 antibody, erlin-2 antibody, Erlin-2 antibody, ER lipid raft associated 2 S homeolog antibody, ER lipid raft associated 2 L homeolog antibody, ERLIN2 antibody, erlin2 antibody, Tsp_03442 antibody, erln2 antibody, Erlin2 antibody, erlin2.S antibody, erlin2.L antibody

Background: ERLIN2 plays an important role in the early steps of the endoplasmic reticulum-associated degradation (ERAD) pathway. It is involved in ITPR1 degradation by the ERAD pathway.
Alias Symbols: C8orf2, Erlin-2, MGC87072, SPFH2, NET32, SPG18
Protein Interaction Partner: TIMM50, TMUB1, SRPRB, CCDC47, RHOT1, SEC61B, ERLIN1, HAX1, TRIM28, UBC, HSP90B1, TCP1, HSPA5, HSPA4, CSE1L, CASP8, CANX, ATP2A2, PSENEN, APH1A, NCSTN, SCAP, SREBF2, SREBF1, PSEN1, INSIG1, AMFR, PPP6R3, STK3, ADRA1D, ADRB2, HDAC11, CLN3, MMS19, UBL4A, FN1,
Protein Size: 339

Molecular Weight: 38 kDa

Gene ID: 11160

NCBI Accession: NM_007175, NP_009106

UniProt: O94905