HNRNPH1 antibody (Middle Region)

Catalog No. ABIN2787702

Product Details anti-HNRNPH1 Antibody

Target: HNRNPH1 (Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Sequence: FLNSTAGASG GAYEHRYVEL FLNSTAGASG GAYGSQMMGG MGLSNQSSYG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HNRPH1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HNRPH1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 449 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HNRNPH1

Target: HNRNPH1 (Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1))

Alternative Name: HNRPH1 (HNRNPH1 Products)

Synonyms: HNRPH antibody, HNRPH1 antibody, hnRNPH antibody, HNRNPH1 antibody, hnrph antibody, hnrnph antibody, hnrph1 antibody, hnrnph2 antibody, MGC78776 antibody, hnrph2 antibody, MGC80081 antibody, MGC130700 antibody, MGC69543 antibody, AI642080 antibody, E430005G16Rik antibody, Hnrnph antibody, Hnrph1 antibody, Hnrph antibody, zgc:77712 antibody, heterogeneous nuclear ribonucleoprotein H1 antibody, heterogeneous nuclear ribonucleoprotein H2 antibody, heterogeneous nuclear ribonucleoprotein H1 S homeolog antibody, heterogeneous nuclear ribonucleoprotein H1 L homeolog antibody, HNRNPH1 antibody, HNRNPH2 antibody, hnrnph1.S antibody, hnrnph1.L antibody, hnrnph1 antibody, Hnrnph1 antibody

Background: HNRPH1 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. This protein has three repeats of quasi-RRM domains that bind to RNAs. It is very similar to the family member HNRPF. This gene is thought to be potentially involved in hereditary lymphedema type I phenotype.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. It is very similar to the family member HNRPF. This gene is thought to be potentially involved in hereditary lymphedema type I phenotype. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DKFZp686A15170, HNRPH, hnRNPH, HNRPH1
Protein Interaction Partner: HUWE1, UBC, FUS, CEP76, CEP250, VCP, TP53, SUMO2, SUMO3, TUBGCP3, STAU1, MDM2, RPA3, RPA2, RPA1, ERG, ASB2, EED, rev, APBB1, AASDHPPT, IPO11, TNPO3, PEG10, PSMD9, PPP3CA, PPP2CA, PIN1, PARK2, PARP1, FBXO6, TARDBP, YWHAQ, ADRB2, IGSF8, ICAM1, CD81, PAN2, U
Protein Size: 449

Molecular Weight: 49 kDa

Gene ID: 3187

NCBI Accession: NM_005520, NP_005511

UniProt: P31943