IVD antibody (N-Term)

Catalog No. ABIN2787703

Product Details anti-IVD Antibody

Target: IVD (Isovaleryl-CoA Dehydrogenase (IVD))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IVD antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: APKAQEIDRS NEFKNLREFW KQLGNLGVLG ITAPVQYGGS GLGYLEHVLV

Predicted Reactivity: Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against IVD. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human IVD

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IVD

Target: IVD (Isovaleryl-CoA Dehydrogenase (IVD))

Alternative Name: IVD (IVD Products)

Synonyms: 1300016K07Rik antibody, 6720455E18Rik antibody, AI463340 antibody, ACAD2 antibody, ATIVD antibody, ISOVALERYL-COA-DEHYDROGENASE antibody, ISOVALERYL-COA-DEHYDROGENASE PRECURSOR antibody, IVDH antibody, isovaleryl-CoA-dehydrogenase antibody, isovaleryl coenzyme A dehydrogenase antibody, isovaleryl-CoA dehydrogenase antibody, isovaleryl-CoA-dehydrogenase antibody, Ivd antibody, IVD antibody

Background: Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia.
Protein Interaction Partner: SUMO2, UBC, SUMO1, NEDD8, TERF2, IVD,
Protein Size: 423

Molecular Weight: 46 kDa

Gene ID: 3712

UniProt: P26440

Pathways: Monocarboxylic Acid Catabolic Process