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TRPC6 antibody (N-Term)

TRPC6 Reactivity: Human, Mouse, Rat, Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2787801
  • Target See all TRPC6 Antibodies
    TRPC6 (Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))
    Binding Specificity
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 26
    • 19
    • 13
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Horse
    Host
    • 23
    • 6
    • 2
    • 1
    Rabbit
    Clonality
    • 27
    • 5
    Polyclonal
    Conjugate
    • 31
    • 1
    This TRPC6 antibody is un-conjugated
    Application
    • 25
    • 15
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    MSQSPAFGPR RGSSPRGAAG AAARRNESQD YLLMDSELGE DGCPQAPLPC
    Predicted Reactivity
    Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against TRPC6. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human TRPC6
    Top Product
    Discover our top product TRPC6 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 931 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TRPC6 (Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))
    Alternative Name
    TRPC6 (TRPC6 Products)
    Synonyms
    FSGS2 antibody, TRP6 antibody, AV025995 antibody, LLHWJM002 antibody, LLHWJM003 antibody, LLHWJM004 antibody, TRP-6 antibody, Trrp6 antibody, mtrp6 antibody, trp6 antibody, bZ1P14.9 antibody, si:rp71-1p14.9 antibody, trpc6 antibody, transient receptor potential cation channel subfamily C member 6 antibody, transient receptor potential cation channel, subfamily C, member 6 antibody, transient receptor potential cation channel, subfamily C, member 6a antibody, TRPC6 antibody, Trpc6 antibody, trpc6a antibody, trpc6 antibody
    Background
    TRPC6 forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
    Alias Symbols: FLJ11098, FLJ14863, FSGS2, TRP6
    Protein Interaction Partner: RNF24, TRPC3, ORAI1, TRPM2, TRPC6, SRC, ITPR3, MX1, FYN, TRPC7, TRPC5, TRPC4, TRPC1, TRPC2, ITPR1,
    Protein Size: 931
    Molecular Weight
    106 kDa
    Gene ID
    7225
    NCBI Accession
    NM_004621, NP_004612
    UniProt
    Q9Y210
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