TMED10 antibody (Middle Region)
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- Target See all TMED10 Antibodies
- TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig, Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TMED10 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- KLKPLEVELR RLEDLSESIV NDFAYMKKRE EEMRDTNEST NTRVLYFSIF
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against TMED10. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human TMED10
- Top Product
- Discover our top product TMED10 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 219 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
- Alternative Name
- TMED10 (TMED10 Products)
- Synonyms
- tmp21 antibody, P24(DELTA) antibody, S31I125 antibody, S31III125 antibody, TMP21 antibody, Tmp-21-I antibody, p23 antibody, 1110014C03Rik antibody, Tmp21 antibody, p24delta1 antibody, fe06g04 antibody, wu:fb98e10 antibody, wu:fe06g04 antibody, zgc:85681 antibody, transmembrane p24 trafficking protein 10 L homeolog antibody, transmembrane p24 trafficking protein 10 antibody, tmed10.L antibody, TMED10 antibody, Tmed10 antibody, tmed10 antibody
- Background
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TMED10 is involved in vesicular protein trafficking.This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Alias Symbols: P24(DELTA), S31I125, S31III125, TMP21, Tmp-21-I, p23
Protein Interaction Partner: UBC, SUMO1, NEDD8, ASB8, RNF2, FBXO6, rev, TMED9, COPZ1, SEC23B, UBL4A, DHODH, ATF2, VCP, PTRF, S100A16, NIT2, PRDX6, SEC22B, EIF3C, VAMP2, COPG1, COPE, COPB2, COPB1, COPA, ARCN1, CDK2, EBNA-LP, RYK, TMED2, PSENEN, APH1A, NCSTN, ARF1, GORASP2,
Protein Size: 219 - Molecular Weight
- 24 kDa
- Gene ID
- 10972
- NCBI Accession
- NM_006827, NP_006818
- UniProt
- P49755
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