BMP6 antibody (N-Term)

Catalog No. ABIN2787814

Product Details anti-BMP6 Antibody

Target: BMP6 (Bone Morphogenetic Protein 6 (BMP6))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DGGSPGRTEQ PPPSPQSSSG FLYRRLKTQE KREMQKEILS VLGLPHRPRP

Predicted Reactivity: Cow: 77%, Human: 100%, Mouse: 83%, Pig: 85%, Rat: 83%

Characteristics: This is a rabbit polyclonal antibody against BMP6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BMP6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 513 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BMP6

Target: BMP6 (Bone Morphogenetic Protein 6 (BMP6))

Alternative Name: BMP6 (BMP6 Products)

Synonyms: BMP6 antibody, zgc:113595 antibody, vgr antibody, vgr-1 antibody, vgr1 antibody, VGR antibody, VGR1 antibody, D13Wsu115e antibody, Vgr1 antibody, bone morphogenetic protein 6 antibody, bone morphogenetic protein 6 S homeolog antibody, BMP6 antibody, bmp6 antibody, bmp6.S antibody, Bmp6 antibody

Background: The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.
Alias Symbols: VGR, VGR1
Protein Interaction Partner: UBC, BMPER, SOSTDC1, CHRDL2, BMPR1B, SMAD5, NCOA3, BMPR1A, BMPR2, ACVR2A, ACVR2B,
Protein Size: 513

Molecular Weight: 57 kDa

Gene ID: 654

NCBI Accession: NM_001718, NP_001709

UniProt: P22004

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process