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Rubicon antibody (Middle Region)

KIAA0226 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2787888
  • Target See all Rubicon (KIAA0226) Antibodies
    Rubicon (KIAA0226) (KIAA0226)
    Binding Specificity
    • 18
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit
    Host
    • 31
    • 2
    Rabbit
    Clonality
    • 31
    • 2
    Polyclonal
    Conjugate
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This Rubicon antibody is un-conjugated
    Application
    • 29
    • 19
    • 14
    • 14
    • 10
    • 9
    • 5
    • 3
    Western Blotting (WB)
    Sequence
    DQEGGGESQL SSVLRRSSFS EGQTLTVTSG AKKSHIRSHS DTSIASRGAP
    Predicted Reactivity
    Cow: 85%, Dog: 85%, Guinea Pig: 92%, Human: 100%, Mouse: 92%, Rabbit: 85%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against KIAA0226. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human KIAA0226
    Top Product
    Discover our top product KIAA0226 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 927 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Rubicon (KIAA0226) (KIAA0226)
    Alternative Name
    KIAA0226 (KIAA0226 Products)
    Synonyms
    RUBICON antibody, 5330403K09 antibody, Kiaa0226 antibody, Rubicon antibody, mKIAA0226 antibody, RUN and cysteine rich domain containing beclin 1 interacting protein antibody, KIAA0226 antibody, RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein antibody, RUBCN antibody, KIAA0226 antibody, Rubcn antibody
    Background
    KIAA0226 negatively regulates endocytic trafficking. KIAA0226 impairs the autophagosome maturation process.KIAA0226 may inhibit PIK3C3 activity.
    Alias Symbols: RUBICON
    Protein Interaction Partner: BECN1, PIK3C3, EXOC8, EXOC2, EXOC1, PIK3R4, UVRAG, YWHAE, SMAD9,
    Protein Size: 927
    Molecular Weight
    103 kDa
    Gene ID
    9711
    NCBI Accession
    NM_001145642, NP_001139114
    Pathways
    Autophagy
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