Rubicon antibody (Middle Region)
-
- Target See all Rubicon (KIAA0226) Antibodies
- Rubicon (KIAA0226) (KIAA0226)
-
Binding Specificity
- Middle Region
- Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This Rubicon antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- DQEGGGESQL SSVLRRSSFS EGQTLTVTSG AKKSHIRSHS DTSIASRGAP
- Predicted Reactivity
- Cow: 85%, Dog: 85%, Guinea Pig: 92%, Human: 100%, Mouse: 92%, Rabbit: 85%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against KIAA0226. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human KIAA0226
- Top Product
- Discover our top product KIAA0226 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 927 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- Rubicon (KIAA0226) (KIAA0226)
- Alternative Name
- KIAA0226 (KIAA0226 Products)
- Synonyms
- RUBICON antibody, 5330403K09 antibody, Kiaa0226 antibody, Rubicon antibody, mKIAA0226 antibody, RUN and cysteine rich domain containing beclin 1 interacting protein antibody, KIAA0226 antibody, RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein antibody, RUBCN antibody, KIAA0226 antibody, Rubcn antibody
- Background
-
KIAA0226 negatively regulates endocytic trafficking. KIAA0226 impairs the autophagosome maturation process.KIAA0226 may inhibit PIK3C3 activity.
Alias Symbols: RUBICON
Protein Interaction Partner: BECN1, PIK3C3, EXOC8, EXOC2, EXOC1, PIK3R4, UVRAG, YWHAE, SMAD9,
Protein Size: 927 - Molecular Weight
- 103 kDa
- Gene ID
- 9711
- NCBI Accession
- NM_001145642, NP_001139114
- Pathways
- Autophagy
-