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SYT1 antibody (Middle Region)

SYT1 Reactivity: Human, Rat, Mouse, Cow, Dog, Rabbit, Zebrafish (Danio rerio), Horse, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2788072
  • Target See all SYT1 Antibodies
    SYT1 (Synaptotagmin I (SYT1))
    Binding Specificity
    • 15
    • 14
    • 9
    • 8
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 83
    • 69
    • 51
    • 11
    • 8
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse, Cow, Dog, Rabbit, Zebrafish (Danio rerio), Horse, Guinea Pig
    Host
    • 95
    • 12
    • 4
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 102
    • 12
    Polyclonal
    Conjugate
    • 64
    • 9
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SYT1 antibody is un-conjugated
    Application
    • 70
    • 41
    • 39
    • 17
    • 14
    • 13
    • 13
    • 11
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    FDRFSKHDII GEFKVPMNTV DFGHVTEEWR DLQSAEKEEQ EKLGDICFSL
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against Syt1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide corresponding to a region of Mouse
    Top Product
    Discover our top product SYT1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 421 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SYT1 (Synaptotagmin I (SYT1))
    Alternative Name
    Syt1 (SYT1 Products)
    Synonyms
    P65 antibody, SVP65 antibody, SYT antibody, CG3139 antibody, D. Syt I antibody, DSYT antibody, DSYT2 antibody, DSypt antibody, DSyt antibody, Dmel\\CG3139 antibody, Droso1 antibody, Dsyt2 antibody, SYT I antibody, SYT1 antibody, Syt antibody, Syt 1 antibody, Syt I antibody, Syt-1 antibody, SytI antibody, dSYT antibody, dsyt1 antibody, dsytI antibody, l(2)23AB1 antibody, l(2)23Ba antibody, l(2)k05909 antibody, syt antibody, syt 1 antibody, syt I antibody, syt-1 antibody, syt1 antibody, sytI antibody, AW124717 antibody, G630098F17Rik antibody, Syti antibody, GB20036 antibody, DKFZP459P193 antibody, svp65 antibody, p65 antibody, wu:fj41c01 antibody, wu:fk56d05 antibody, zgc:92899 antibody, synaptotagmin 1 antibody, Synaptotagmin 1 antibody, synaptotagmin I antibody, synaptotagmin-1 antibody, synaptotagmin, p65 antibody, synaptotagmin Ia antibody, synaptotagmin 1 L homeolog antibody, SYT1 antibody, Syt1 antibody, Tsp_06980 antibody, Tsp_08220 antibody, syt1 antibody, LOC100533340 antibody, syt1a antibody, syt1.L antibody
    Background
    Syt1 may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner, these are neurexins, syntaxin and AP2.
    Alias Symbols: AW124717, G630098F17Rik, SytI
    Protein Interaction Partner: Lrp1b, CALM1, Syp, Htt,
    Protein Size: 421
    Molecular Weight
    47 kDa
    Gene ID
    20979
    NCBI Accession
    NM_009306, NP_033332
    UniProt
    P46096
    Pathways
    Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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