Calnexin antibody (Middle Region)
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- Target See all Calnexin (CANX) Antibodies
- Calnexin (CANX)
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, Horse, Goat, Zebrafish (Danio rerio), Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Calnexin antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LVDQSVVNSG NLLNDMTPPV NPSREIEDPE DRKPEDWDER PKIPDPEAVK
- Predicted Reactivity
- Cow: 100%, Dog: 93%, Goat: 79%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 80%, Zebrafish: 86%
- Characteristics
- This is a rabbit polyclonal antibody against CANX. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CANX
- Top Product
- Discover our top product CANX Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 592 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Calnexin (CANX)
- Alternative Name
- CANX (CANX Products)
- Synonyms
- CNX antibody, IP90 antibody, P90 antibody, 1110069N15Rik antibody, AI988026 antibody, Cnx antibody, D11Ertd153e antibody, canx antibody, clgn antibody, clnx antibody, cnx antibody, PP90 antibody, zgc:63524 antibody, wu:fe06b12 antibody, CANX antibody, calnexin antibody, CalNeXin antibody, calnexin L homeolog antibody, CANX antibody, Canx antibody, cnx-1 antibody, canx.L antibody, canx antibody, LOC100283947 antibody
- Background
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This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.
Alias Symbols: CNX, FLJ26570, IP90, P90
Protein Interaction Partner: ERLIN2, HUWE1, UBC, TRAF6, SUMO2, TOR1A, STAU1, MDM2, LGR4, WWOX, NPHS1, RPA3, RPA2, RPA1, SUZ12, RNF2, BMI1, FBXO6, PTGIR, ADRB2, PDIA3, CLN5, YIPF3, SMURF2, env, PGRMC1, BCAP31, UBL4A, SERPINA1, MTNR1A, CSNK2A1, ATF2, CFTR, VCP, PKD2, LDLR, ASGR1, KCNH2
Protein Size: 592 - Molecular Weight
- 65 kDa
- Gene ID
- 821
- NCBI Accession
- NM_001746, NP_001737
- UniProt
- P27824
- Pathways
- MAPK Signaling, Thyroid Hormone Synthesis
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