MAGEA2 antibody (N-Term)

Catalog No. ABIN2788250

Product Details anti-MAGEA2 Antibody

Target: MAGEA2 (Melanoma Antigen Family A, 2 (MAGEA2))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LGLVGAQAPA TEEQQTASSS STLVEVTLGE VPAADSPSPP HSPQGASSFS

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against MAGEA2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAGEA2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 314 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAGEA2

Target: MAGEA2 (Melanoma Antigen Family A, 2 (MAGEA2))

Alternative Name: MAGEA2 (MAGEA2 Products)

Synonyms: Mage-a2 antibody, MAGEA2 antibody, CT1.2 antibody, MAGE2 antibody, MAGEA2A antibody, melanoma antigen, family A, 2 antibody, melanoma-associated antigen 2 antibody, MAGE family member A2 antibody, Magea2 antibody, LOC706218 antibody, MAGEA2 antibody

Background: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This gene has two identical copies at different loci. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: CT1.2, MAGE2, MAGEA2A, MAGEA2B, MGC131923
Protein Interaction Partner: UBC, PML, TRIM28, HDAC3, TP53,
Protein Size: 314

Molecular Weight: 35 kDa

Gene ID: 4101

NCBI Accession: NM_005361, NP_005352

UniProt: P43356