CDKL5 antibody (C-Term)

Catalog No. ABIN2788268

Product Details anti-CDKL5 Antibody

Target: CDKL5 (Cyclin-Dependent Kinase-Like 5 (CDKL5))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDKL5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SQASGGSSNI RQEPAPKGRP ALQLPDGGCD GRRQRHHSGP QDRRFMLRTT

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CDKL5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CDKL5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1030 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDKL5

Target: CDKL5 (Cyclin-Dependent Kinase-Like 5 (CDKL5))

Alternative Name: CDKL5 (CDKL5 Products)

Synonyms: issx antibody, stk9 antibody, EIEE2 antibody, ISSX antibody, STK9 antibody, BC038161 antibody, Stk9 antibody, cyclin dependent kinase like 5 antibody, cyclin-dependent kinase-like 5 antibody, CDKL5 antibody, cdkl5 antibody, Cdkl5 antibody

Background: CDKL5 is a member of Ser/Thr protein kinase family. This protein is a phosphorylated protein with protein kinase activity. Mutations in this CDKL5 gene have been associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome, and Rett syndrome (RTT).
Alias Symbols: ISSX, STK9, EIEE2
Protein Interaction Partner: CDKL5, PRKG2, Dlg4, SKIV2L, MGMT, MECP2,
Protein Size: 1030

Molecular Weight: 115 kDa

Gene ID: 6792

NCBI Accession: NM_003159, NP_003150

UniProt: O76039

Pathways: Regulation of Cell Size