CNR1 antibody (N-Term)

Catalog No. ABIN2788297

Product Details anti-CNR1 Antibody

Target: CNR1 (Cannabinoid Receptor 1 (CNR1))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Dog, Horse, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNR1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ADQVNITEFY NKSLSSFKEN EENIQCGENF MDIECFMVLN PSQQLAIAVL

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CNR1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CNR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 411 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CNR1

Target: CNR1 (Cannabinoid Receptor 1 (CNR1))

Alternative Name: CNR1 (CNR1 Products)

Synonyms: CANN6 antibody, CB-R antibody, CB1 antibody, CB1A antibody, CB1K5 antibody, CB1R antibody, CNR antibody, SKR6R antibody, cnr1-A antibody, cannabinoid receptor 1 antibody, cannabinoid receptor 1 (brain) antibody, cannabinoid receptor 1 (brain) S homeolog antibody, CNR1 antibody, Cnr1 antibody, cnr1 antibody, cnr1.S antibody

Background: This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana.
Alias Symbols: CANN6, CB-R, CB1, CB1A, CB1K5, CB1R, CNR
Protein Interaction Partner: RAP1GAP, HCRTR1, MET, GNAI3, GNAI2, GNA15, GNAI1, HIST4H4, PAX3,
Protein Size: 411

Molecular Weight: 45 kDa

Gene ID: 1268

NCBI Accession: NM_016083, NP_057167

UniProt: P21554

Pathways: Feeding Behaviour