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F2RL1 antibody (C-Term)

F2RL1 Reactivity: Human, Rat, Dog, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2788314
  • Target See all F2RL1 Antibodies
    F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
    Binding Specificity
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 35
    • 9
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Dog, Guinea Pig
    Host
    • 34
    • 6
    Rabbit
    Clonality
    • 32
    • 8
    Polyclonal
    Conjugate
    • 24
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This F2RL1 antibody is un-conjugated
    Application
    • 19
    • 16
    • 13
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    Western Blotting (WB)
    Sequence
    VSHDFRDHAK NALLCRSVRT VKQMQVSLTS KKHSRKSSSY SSSSTTVKTS
    Predicted Reactivity
    Dog: 93%, Guinea Pig: 86%, Human: 100%, Rat: 86%
    Characteristics
    This is a rabbit polyclonal antibody against F2RL1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product F2RL1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 397 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Yau, Liu, Fairlie: "Toward drugs for protease-activated receptor 2 (PAR2)." in: Journal of medicinal chemistry, Vol. 56, Issue 19, pp. 7477-97, (2013) (PubMed).

  • Target
    F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
    Alternative Name
    F2RL1 (F2RL1 Products)
    Synonyms
    par2 antibody, GPR11 antibody, PAR2 antibody, Gpcr11 antibody, PAR-2 antibody, Par2 antibody, Par-2 antibody, Proteinase-activated receptor 2 antibody, F2R like trypsin receptor 1 antibody, coagulation factor II (thrombin) receptor-like 1 antibody, par2 antibody, F2RL1 antibody, F2rl1 antibody
    Background
    Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83 % identical to the mouse receptor sequence.
    Alias Symbols: GPR11, PAR2
    Protein Interaction Partner: BIRC5, COPS5, UBC, Cbl, ST14, GPRASP1, PRTN3, F2, PLG, ELANE, CTSG, CAPN2, CAPN1,
    Protein Size: 397
    Molecular Weight
    44 kDa
    Gene ID
    2150
    NCBI Accession
    NM_005242, NP_005233
    UniProt
    P55085
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome
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