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CTSC antibody (N-Term)

CTSC Reactivity: Human, Rat, Pig, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2788337
  • Target See all CTSC Antibodies
    CTSC (Cathepsin C (CTSC))
    Binding Specificity
    • 15
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 31
    • 18
    • 11
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Pig, Rabbit
    Host
    • 49
    • 5
    • 1
    Rabbit
    Clonality
    • 52
    • 2
    Polyclonal
    Conjugate
    • 28
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CTSC antibody is un-conjugated
    Application
    • 44
    • 21
    • 13
    • 13
    • 8
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    VNIAHLKNSQ EKYSNRLYKY DHNFVKAINA IQKSWTATTY MEYETLTLGD
    Predicted Reactivity
    Human: 100%, Pig: 79%, Rabbit: 90%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against CTSC. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human CTSC
    Top Product
    Discover our top product CTSC Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CTSC (Cathepsin C (CTSC))
    Alternative Name
    CTSC (CTSC Products)
    Synonyms
    CPPI antibody, DPP-I antibody, DPP1 antibody, DPPI antibody, HMS antibody, JP antibody, JPD antibody, PALS antibody, PDON1 antibody, PLS antibody, MGC69126 antibody, MGC107782 antibody, AI047818 antibody, CATC antibody, cb912 antibody, ik:tdsubc_1h2 antibody, sb:cb146 antibody, wu:fb34g12 antibody, wu:fj58d01 antibody, cathepsin C antibody, cathepsin C L homeolog antibody, cathepsin CPC1 antibody, CTSC antibody, ctsc.L antibody, ctsc antibody, TP03_0357 antibody, CMU_003360 antibody, CPC1 antibody, NAEGRDRAFT_80477 antibody, NAEGRDRAFT_37577 antibody, Ctsc antibody, Smp_183330 antibody
    Background
    CTSC is a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in CTSC have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.
    Protein Interaction Partner: SUMO1, UBC, NEDD8, ARMC9, ANKMY2, ARIH1, UBA2, ADSL, FBXO6, XRN2, CAPN1, CD81, CTSC, CTSL,
    Protein Size: 463
    Molecular Weight
    50 kDa
    Gene ID
    1075
    UniProt
    P53634
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