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CTSC antibody (N-Term)
CTSC
Reactivity: Human, Rat, Pig, Rabbit
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CTSC Antibody
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Target
See all CTSC Antibodies
CTSC
(Cathepsin C (CTSC))
Binding Specificity
All epitopes for CTSC antibodies
N-Term
Reactivity
All reactivities for CTSC antibodies
Human, Rat, Pig, Rabbit
Host
All hosts for CTSC antibodies
Rabbit
Clonality
All clonalities for CTSC antibodies
Polyclonal
Conjugate
All conjugates for CTSC antibodies
This CTSC antibody is un-conjugated
Application
All applications for CTSC antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Sequence
VNIAHLKNSQ EKYSNRLYKY DHNFVKAINA IQKSWTATTY MEYETLTLGD
Predicted Reactivity
Human: 100%, Pig: 79%, Rabbit: 90%, Rat: 100%
Characteristics
This is a rabbit polyclonal antibody against CTSC. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human CTSC
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Discover our top product CTSC Primary Antibody
Alternatives
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Application Details
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Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for CTSC
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Target
CTSC
(Cathepsin C (CTSC))
Alternative Name
CTSC (CTSC Products )
Synonyms
CPPI antibody, DPP-I antibody, DPP1 antibody, DPPI antibody, HMS antibody, JP antibody, JPD antibody, PALS antibody, PDON1 antibody, PLS antibody, MGC69126 antibody, MGC107782 antibody, AI047818 antibody, CATC antibody, cb912 antibody, ik:tdsubc_1h2 antibody, sb:cb146 antibody, wu:fb34g12 antibody, wu:fj58d01 antibody, cathepsin C antibody, cathepsin C L homeolog antibody, cathepsin CPC1 antibody, CTSC antibody, ctsc.L antibody, ctsc antibody, TP03_0357 antibody, CMU_003360 antibody, CPC1 antibody, NAEGRDRAFT_80477 antibody, NAEGRDRAFT_37577 antibody, Ctsc antibody, Smp_183330 antibody
Background
CTSC is a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in CTSC have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Protein Interaction Partner: SUMO1, UBC, NEDD8, ARMC9, ANKMY2, ARIH1, UBA2, ADSL, FBXO6, XRN2, CAPN1, CD81, CTSC, CTSL, Protein Size: 463
Molecular Weight
50 kDa
Gene ID
1075
UniProt
P53634
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