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CYP11B1 antibody (Middle Region)

CYP11B1 Reactivity: Human, Rat, Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2788350
  • Target See all CYP11B1 Antibodies
    CYP11B1 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 1 (CYP11B1))
    Binding Specificity
    • 15
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 36
    • 17
    • 16
    • 1
    • 1
    • 1
    Human, Rat, Horse
    Host
    • 36
    • 2
    Rabbit
    Clonality
    • 37
    • 1
    Polyclonal
    Conjugate
    • 20
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP11B1 antibody is un-conjugated
    Application
    • 31
    • 13
    • 13
    • 12
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    LALFGERLGL VGHSPSSASL NFLHALEVMF KSTVQLMFMP RSLSRWTSPK
    Predicted Reactivity
    Horse: 79%, Human: 100%, Rat: 79%
    Characteristics
    This is a rabbit polyclonal antibody against CYP11B1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human CYP11B1
    Top Product
    Discover our top product CYP11B1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 503 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CYP11B1 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 1 (CYP11B1))
    Alternative Name
    CYP11B1 (CYP11B1 Products)
    Synonyms
    CPN1 antibody, CYP11B antibody, FHI antibody, P450C11 antibody, AA389061 antibody, Cyp11b antibody, Cyp11b-1 antibody, Cp11ba antibody, RATCP11BA antibody, P450c11 antibody, cytochrome P450, family 11, subfamily B, polypeptide 1 antibody, cytochrome P450 family 11 subfamily B member 1 antibody, cytochrome P450, family 11, subfamily b, polypeptide 1 antibody, cytochrome P450, subfamily XI B, polypeptide 1 antibody, CYP11B1 antibody, Cyp11b1 antibody
    Background
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.
    Alias Symbols: CPN1, CYP11B, DKFZp686B05283, FHI, FLJ36771, P450C11
    Protein Interaction Partner: CYP11B2,
    Protein Size: 503
    Molecular Weight
    55 kDa
    Gene ID
    1584
    NCBI Accession
    NM_000497, NP_000488
    UniProt
    P15538
    Pathways
    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis
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