CYP24A1 antibody (C-Term)
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- Target See all CYP24A1 Antibodies
- CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Dog, Rabbit, Guinea Pig, Cow, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CYP24A1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LNTKVWQDHT LAWDTIFKSV KACIDNRLEK YSQQPSADFL CDIYHQNRLS
- Predicted Reactivity
- Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 86%
- Characteristics
- This is a rabbit polyclonal antibody against CYP24A1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human CYP24A1
- Top Product
- Discover our top product CYP24A1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 514 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))
- Alternative Name
- CYP24A1 (CYP24A1 Products)
- Background
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CYP24A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system.
Alias Symbols: CP24, CYP24, MGC126273, MGC126274, P450-CC24, HCAI
Protein Interaction Partner: Dlg4, UBC,
Protein Size: 514 - Molecular Weight
- 55 kDa
- Gene ID
- 1591
- NCBI Accession
- NM_000782, NP_000773
- UniProt
- Q07973
- Pathways
- Metabolism of Steroid Hormones and Vitamin D
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