GADD45A antibody (C-Term)

Catalog No. ABIN2788360

Product Details anti-GADD45A Antibody

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Binding Specificity: C-Term

Reactivity: Human, Cow, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GADD45A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LRVSNPGRLA ELLLLETDAG PAASEGAEQP PDLHCVLVTN PHSSQWKDPA

Predicted Reactivity: Cow: 100%, Horse: 79%, Human: 100%, Pig: 93%, Rabbit: 86%

Characteristics: This is a rabbit polyclonal antibody against GADD45A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GADD45A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 165 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GADD45A

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Alternative Name: GADD45A (GADD45A Products)

Synonyms: MGC53491 antibody, zgc:91795 antibody, gadd45a antibody, GADD45A antibody, ddit1 antibody, gadd45 antibody, GADD45 antibody, AA545191 antibody, Ddit1 antibody, DDIT1 antibody, Gadd45 antibody, growth arrest and DNA damage inducible alpha L homeolog antibody, growth arrest and DNA-damage-inducible, alpha, b antibody, growth arrest and DNA damage inducible alpha antibody, growth arrest and DNA damage-inducible protein 45 antibody, growth arrest and DNA-damage-inducible 45 alpha antibody, growth arrest and DNA-damage-inducible, alpha antibody, gadd45a.L antibody, gadd45ab antibody, GADD45A antibody, gadd45a antibody, GADD45 antibody, Gadd45a antibody

Background: GADD45A responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of GADD45A gene is mediated by both p53-dependent and -independent mechanisms.
Alias Symbols: DDIT1, GADD45
Protein Interaction Partner: ING4, UBC, AURKA, STAT3, PCNA, MTOR, CDK1, APEX1, DCTN2, RPS7, MDM2, MAPK1, TIAL1, HNRNPA0, SH3GLB1, PTPRK, PSMC3, NUCB2, CDK11A, ASCC2, FAS, CCNB1, DNMT1, JMJD1C, UBR1, SYNE4, MIDN, IGSF21, FBN3, FAM83D, MICAL1, SPTBN4, NRBP1, DNAJC13, ZHX1, C14orf1, ADA
Protein Size: 165

Molecular Weight: 18 kDa

Gene ID: 1647

NCBI Accession: NM_001924, NP_001915

UniProt: P24522

Pathways: p53 Signaling, Cell Division Cycle