CAPNS2 antibody (N-Term)

Catalog No. ABIN2788439

Product Details anti-CAPNS2 Antibody

Target: CAPNS2 (Calpain, Small Subunit 2 (CAPNS2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Pig, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAPNS2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GRNIGGIVGG IVNFISEAAA AQYTPEPPPT QQHFTSVEAS ESEEVRRFRQ

Predicted Reactivity: Cow: 75%, Dog: 75%, Guinea Pig: 75%, Horse: 75%, Human: 100%, Mouse: 93%, Pig: 79%, Rabbit: 93%, Rat: 75%, Sheep: 82%

Characteristics: This is a rabbit polyclonal antibody against CAPNS2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CAPNS2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 248 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CAPNS2

Target: CAPNS2 (Calpain, Small Subunit 2 (CAPNS2))

Alternative Name: CAPNS2 (CAPNS2 Products)

Synonyms: 2310005G05Rik antibody, 30K-2 antibody, calpain, small subunit 2 antibody, calpain small subunit 2 antibody, Capns2 antibody, CAPNS2 antibody

Background: CAPNS2 is a calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity.
Alias Symbols: MGC12536, MGC14804
Protein Interaction Partner: APP, CAPN2,
Protein Size: 248

Molecular Weight: 28 kDa

Gene ID: 84290

NCBI Accession: NM_032330, NP_115706

UniProt: Q96L46