HPSE antibody (N-Term)

Catalog No. ABIN2788568

Product Details anti-HPSE Antibody

Target: HPSE (Heparanase (HPSE))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HPSE antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KLRLEWPYQE QLLLREHYQK KFKNSTYSRS SVDVLYTFAN CSGLDLIFGL

Predicted Reactivity: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 92%, Rabbit: 79%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against HPSE. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HPSE

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 543 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HPSE

Target: HPSE (Heparanase (HPSE))

Alternative Name: HPSE (HPSE Products)

Synonyms: im:7144134 antibody, hpa antibody, hpa1 antibody, hpr1 antibody, hpse1 antibody, hse1 antibody, HPSE antibody, HPA antibody, HPA1 antibody, HPR1 antibody, HPSE1 antibody, HSE1 antibody, Hpa antibody, Hpr1 antibody, Hep antibody, heparanase antibody, HPSE antibody, hpse antibody, Hpse antibody

Background: Heparan sulfate proteoglycans (HSPGs) are major components of the basement membrane and extracellular matrix. Heparanases, like HSPE, are endoglycosidases that cleave the heparan sulfate side chain of HSPGs to permit the remodeling of the extracellular matrix for cell movement or the release of bioactive molecules from the extracellular matrix or cell surface.
Alias Symbols: HPA, HPR1, HPSE1, HSE1, HPA1
Protein Interaction Partner: HPSE,
Protein Size: 543

Molecular Weight: 61 kDa

Gene ID: 10855

NCBI Accession: NM_006665, NP_006656

UniProt: Q9Y251

Pathways: Glycosaminoglycan Metabolic Process