ENO2/NSE antibody (Middle Region)

Catalog No. ABIN2788574

Product Details anti-ENO2/NSE Antibody

Target: ENO2/NSE (ENO2) (Enolase 2 (Gamma, Neuronal) (ENO2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Cow, Horse, Goat, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENO2/NSE antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ESFRDAMRLG AEVYHTLKGV IKDKYGKDAT NVGDEGGFAP NILENSEALE

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against ENO2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ENO2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 434 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ENO2/NSE antibody (ABIN2788574)

Choudhuri, Maitra, Evans: "Translation initiation factor eIF3h targets specific transcripts to polysomes during embryogenesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 24, pp. 9818-23, (2013) (PubMed).

Target Details for ENO2/NSE

Target: ENO2/NSE (ENO2) (Enolase 2 (Gamma, Neuronal) (ENO2))

Alternative Name: ENO2 (ENO2 Products)

Synonyms: ENO2 antibody, DKFZp459B1817 antibody, NSE antibody, AI837106 antibody, D6Ertd375e antibody, Eno-2 antibody, RNEN3 antibody, eno3 antibody, wu:fc09h05 antibody, zgc:92418 antibody, enolase 2 antibody, enolase 2 (gamma, neuronal) antibody, enolase 2, gamma neuronal antibody, enolase 2, gamma, neuronal antibody, ENO2 antibody, Eno2 antibody, eno2 antibody

Background: This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates.
Alias Symbols: NSE
Protein Interaction Partner: EXOC5, UBC, ASB9, ASB5, GMPS, RCN1, RAB1A, PNP, COASY, EFHD2, A2M, AKT1, UBD, CDK2, CAND1, CUL1, CUL2, CUL3, CUL4B, ACD, TINF2, POT1, TERF1, PPP1CC, PPP1CA, SUMO1, SUMO4, HABP4, NAT9, C6orf47, C16orf45, SIGIRR, ENSA, SNUPN, ST3GAL2, UBE2C, IL17B, ANXA11,
Protein Size: 434

Molecular Weight: 47 kDa

Gene ID: 2026

NCBI Accession: NM_001975, NP_001966

UniProt: P09104