AKR1D1 antibody (Middle Region)
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- Target See all AKR1D1 Antibodies
- AKR1D1 (Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Rat, Mouse, Cow, Rabbit, Horse, Pig, Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This AKR1D1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- YVDLYIIEVP MAFKPGDEIY PRDENGKWLY HKSNLCATWE AMEACKDAGL
- Predicted Reactivity
- Cow: 86%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 86%, Rabbit: 100%, Rat: 77%
- Characteristics
- This is a rabbit polyclonal antibody against AKR1D1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human AKR1D1
- Top Product
- Discover our top product AKR1D1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 326 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- AKR1D1 (Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))
- Alternative Name
- AKR1D1 (AKR1D1 Products)
- Background
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The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet.
Alias Symbols: 3o5bred, CBAS2, SRD5B1
Protein Size: 326 - Molecular Weight
- 37 kDa
- Gene ID
- 6718
- NCBI Accession
- NM_005989, NP_005980
- UniProt
- P51857
- Pathways
- Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process
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