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CYB5R3 antibody (C-Term)

CYB5R3 Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Rabbit, Guinea Pig, Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2788600
  • Target See all CYB5R3 Antibodies
    CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))
    Binding Specificity
    • 8
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat, Dog, Cow, Pig, Rabbit, Guinea Pig, Horse
    Host
    • 46
    • 7
    • 3
    Rabbit
    Clonality
    • 51
    • 5
    Polyclonal
    Conjugate
    • 28
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYB5R3 antibody is un-conjugated
    Application
    • 45
    • 24
    • 19
    • 14
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    Western Blotting (WB)
    Sequence
    IRAIMKDPDD HTVCHLLFAN QTEKDILLRP ELEELRNKHS ARFKLWYTLD
    Predicted Reactivity
    Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 86%
    Characteristics
    This is a rabbit polyclonal antibody against CYB5R3. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human CYB5R3
    Top Product
    Discover our top product CYB5R3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 301 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))
    Alternative Name
    CYB5R3 (CYB5R3 Products)
    Synonyms
    B5R antibody, DIA1 antibody, Dia1 antibody, Nadhcb5 antibody, RNNADHCB5 antibody, 0610016L08Rik antibody, 2500002N19Rik antibody, C85115 antibody, Dia-1 antibody, WU:AL591952.1-001 antibody, WU:AL591952.1-002 antibody, WU:AL591952.1-003 antibody, WU:Cyb5r3 antibody, fc32h03 antibody, zgc:77071 antibody, wu:fc32h03 antibody, dia1 antibody, CB5R antibody, DDBDRAFT_0218707 antibody, DDBDRAFT_0266821 antibody, DDB_0218707 antibody, DDB_0266821 antibody, cytochrome b5 reductase 3 antibody, cytochrome b5 reductase 3 L homeolog antibody, NADH-cytochrome b5 reductase antibody, CYB5R3 antibody, Cyb5r3 antibody, cyb5r3 antibody, cyb5r3.L antibody, CNM00240 antibody, Tb11.47.0018 antibody, cyb5r1 antibody
    Background
    This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias.
    Alias Symbols: B5R, DIA1
    Protein Interaction Partner: SUMO2, PARK2, UBC, SLC1A5, SDHA, RPS7, HSPA1L, CDK2, SPP1, CYB5R3, CYB5A, HBG2, CYCS, ESR1,
    Protein Size: 301
    Molecular Weight
    34 kDa
    Gene ID
    1727
    NCBI Accession
    NM_000398, NP_000389
    UniProt
    P00387
    Pathways
    SARS-CoV-2 Protein Interactome
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