IDS antibody (N-Term)

Catalog No. ABIN2788631

Product Details anti-IDS Antibody

Target: IDS (Iduronate 2-Sulfatase (IDS))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDS antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SFPPYHPSSE KYENTKTCRG PDGELHANLL CPVDVLDVPE GTLPDKQSTE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against IDS. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IDS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 550 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IDS

Target: IDS (Iduronate 2-Sulfatase (IDS))

Alternative Name: IDS (IDS Products)

Synonyms: mps2 antibody, sids antibody, zgc:158245 antibody, MPS2 antibody, SIDS antibody, AW214631 antibody, iduronate 2-sulfatase antibody, IDS antibody, CpipJ_CPIJ004938 antibody, ids antibody, Ids antibody

Background: Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.
Alias Symbols: MPS2, SIDS
Protein Interaction Partner: Dlg4,
Protein Size: 550

Molecular Weight: 59 kDa

Gene ID: 3423

NCBI Accession: NM_000202, NP_000193

UniProt: P22304

Pathways: Glycosaminoglycan Metabolic Process