CHRM1 antibody (C-Term)

Catalog No. ABIN2788654

Product Details anti-CHRM1 Antibody

Target: CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

Binding Specificity: C-Term

Reactivity: Rat, Human, Mouse, Dog, Rabbit, Cow, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRM1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VKRPTKKGRD RAGKGQKPRG KEQLAKRKTF SLVKEKKAAR TLSAILLAFI

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CHRM1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CHRM1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 460 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHRM1

Target: CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

Alternative Name: CHRM1 (CHRM1 Products)

Synonyms: M1 antibody, CHRM1 antibody, HM1 antibody, M1R antibody, mAChR antibody, Chrm-1 antibody, cholinergic receptor muscarinic 1 antibody, cholinergic receptor, muscarinic 1 antibody, cholinergic receptor, muscarinic 1, CNS antibody, CHRM1 antibody, Chrm1 antibody

Background: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.
Alias Symbols: HM1, M1, M1R, MGC30125
Protein Interaction Partner: CDC14A, GPRASP2, GPRASP1, Dlg4, GNAI2,
Protein Size: 460

Molecular Weight: 51 kDa

Gene ID: 1128

NCBI Accession: NM_000738, NP_000729

UniProt: P11229

Pathways: Synaptic Membrane