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MEK1 antibody (N-Term)

MAP2K1 Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2788667
  • Target See all MEK1 (MAP2K1) Antibodies
    MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
    Binding Specificity
    • 42
    • 28
    • 28
    • 22
    • 22
    • 20
    • 19
    • 19
    • 18
    • 16
    • 15
    • 14
    • 11
    • 11
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    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 363
    • 194
    • 193
    • 32
    • 29
    • 17
    • 12
    • 12
    • 12
    • 10
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig
    Host
    • 339
    • 21
    • 3
    • 2
    • 2
    Rabbit
    Clonality
    • 292
    • 75
    Polyclonal
    Conjugate
    • 176
    • 25
    • 22
    • 17
    • 12
    • 12
    • 12
    • 12
    • 12
    • 12
    • 11
    • 10
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This MEK1 antibody is un-conjugated
    Application
    • 242
    • 124
    • 101
    • 68
    • 66
    • 47
    • 33
    • 30
    • 25
    • 15
    • 11
    • 10
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    KKPTPIQLNP APDGSAVNGT SSAETNLEAL QKKLEELELD EQQRKRLEAF
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against Map2k1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Map2k1
    Top Product
    Discover our top product MAP2K1 Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
    Alternative Name
    Map2k1 (MAP2K1 Products)
    Synonyms
    Mek1 antibody, CFC3 antibody, MAPKK1 antibody, MEK1 antibody, MKK1 antibody, PRKMK1 antibody, MEKK1 antibody, Prkmk1 antibody, mek-2 antibody, si:ch211-242m18.2 antibody, wu:fj56a12 antibody, wu:fj61b01 antibody, zgc:56557 antibody, ATMEK1 antibody, F20B18.180 antibody, F20B18_180 antibody, MAP kinase/ ERK kinase 1 antibody, MITOGEN ACTIVATED PROTEIN KINASE KINASE antibody, MITOGEN ACTIVATED PROTEIN KINASE KINASE 1 antibody, NMAPKK antibody, MEK antibody, mitogen activated protein kinase kinase 1 antibody, mitogen-activated protein kinase kinase 1 antibody, mitogen-activated protein kinase kinase 1 L homeolog antibody, MAP kinase/ ERK kinase 1 antibody, Map2k1 antibody, MAP2K1 antibody, map2k1.L antibody, map2k1 antibody, MEK1 antibody
    Background
    Map2k1 is a dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway.Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation.
    Alias Symbols: MAPKK1, MEKK1, Mek1, Prkmk1
    Protein Interaction Partner: Eed, Myod1, Map3k1, Cflar, Foxp3, Ksr1, Brap, Grin2b, Grin1, Nek10, Raf1, CPNE1, CPNE4,
    Protein Size: 393
    Molecular Weight
    43 kDa
    Gene ID
    26395
    NCBI Accession
    NM_008927, NP_032953
    UniProt
    P31938
    Pathways
    MAPK Signaling, RTK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
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