Desmoglein 3 antibody (C-Term)
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- Target See all Desmoglein 3 (DSG3) Antibodies
- Desmoglein 3 (DSG3)
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Desmoglein 3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- KKLAEISLGV DGEGKEVQPP SKDSGYGIES CGHPIEVQQT GFVKCQTLSG
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against DSG3. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human DSG3
- Top Product
- Discover our top product DSG3 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 999 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Desmoglein 3 (DSG3)
- Alternative Name
- DSG3 (DSG3 Products)
- Synonyms
- DSG3 antibody, CDHF6 antibody, PVA antibody, bal antibody, balding antibody, desmoglein 3 antibody, DSG3 antibody, Dsg3 antibody
- Background
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Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
Alias Symbols: CDHF6, DKFZp686P23184, PVA
Protein Interaction Partner: WWOX, PKP3, CASP3, JUP, FURIN,
Protein Size: 999 - Molecular Weight
- 102 kDa
- Gene ID
- 1830
- NCBI Accession
- NM_001944, NP_001935
- UniProt
- P32926
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