SRSF2 antibody (C-Term)

Catalog No. ABIN2788766

Product Details anti-SRSF2 Antibody

Target: SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRSF2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KSKSSSVSRS RSRSRSRSRS RSPPPVSKRE SKSRSRSKSP PKSPEEEGAV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against SFRS2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 221 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SRSF2

Target: SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))

Alternative Name: SFRS2 (SRSF2 Products)

Synonyms: PR264 antibody, SC-35 antibody, SC35 antibody, SFRS2 antibody, SFRS2A antibody, SRp30b antibody, D11Wsu175e antibody, MRF-1 antibody, Pr264 antibody, Sfrs10 antibody, Sfrs2 antibody, pr264 antibody, sc-35 antibody, sc35 antibody, sfrs2 antibody, sfrs2a antibody, srp30b antibody, serine and arginine rich splicing factor 2 antibody, serine/arginine-rich splicing factor 2 antibody, serine/arginine-rich splicing factor 2 L homeolog antibody, SRSF2 antibody, Srsf2 antibody, srsf2.L antibody

Background: The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene.
Alias Symbols: PR264, SC-35, SC35, SFRS2A, SRp30b, SFRS2
Protein Interaction Partner: KRT40, LZTS2, CEP72, HUWE1, TCF4, TRIM27, KRT31, GOLGA2, EED, PARK2, SRPK2, SRPK1, YWHAE, CIR1, UBC, U2AF1, TRA2B, SRSF4, SRSF3, SRSF2, CSNK2A1, CDK6, EIF4A3, MAGOH, PAXIP1, LIG4, ESR1, BARD1, NUBP2, UBA2, HNRNPDL, ATP6V1F, RUVBL1, XPO1, UBE2B, TTN, TPM4,
Protein Size: 221

Molecular Weight: 25 kDa

Gene ID: 6427

NCBI Accession: NM_003016, NP_003007

UniProt: Q01130