ABI2 antibody (N-Term)

Catalog No. ABIN2788799

Product Details anti-ABI2 Antibody

Target: ABI2 (Abl-Interactor 2 (ABI2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog, Horse, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABI2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MLLEEEIPGG RRALFDSYTN LERVADYCEN NYIQSADKQR ALEETKAYTT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Yeast: 83%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against ABI2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ABI2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 475 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ABI2

Target: ABI2 (Abl-Interactor 2 (ABI2))

Alternative Name: ABI2 (ABI2 Products)

Synonyms: ABI-2 antibody, ABI2B antibody, AIP-1 antibody, AblBP3 antibody, SSH3BP2 antibody, argBPIA antibody, argBPIB antibody, 8430425M24Rik antibody, AI839867 antibody, C130078H13 antibody, abl interactor 2 antibody, abl-interactor 2 antibody, ABI2 antibody, abi2 antibody, Abi2 antibody

Background: ABI2 may act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. ABI2 is a part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. It regulates ABL1/c-Abl-mediated phosphorylation of MENA.
Alias Symbols: ABI-2, ABI2B, AIP-1, AblBP3, SSH3BP2, argBPIA, argBPIB
Protein Interaction Partner: CCDC36, MRFAP1L1, EGLN3, IFT20, PRAM1, CCDC102B, ARMC7, GCC1, MRPL44, VARS2, KIAA1217, CCHCR1, PRR16, BLOC1S6, TFIP11, NUP62, TRIM32, EFS, STAM2, ABI2, PPIF, ARHGAP32, HOMER3, HGS, EIF3H, NCK2, WIPF1, VASP, TRIP6, SDCBP, PRKAA2, PRKAA1, PIN1, LMO2, KRT33B
Protein Size: 475

Molecular Weight: 52 kDa

Gene ID: 10152

NCBI Accession: NM_005759, NP_005750

UniProt: Q9NYB9