MMACHC antibody (C-Term)
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- Target See all MMACHC Antibodies
- MMACHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MMACHC antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- IALLEGFNFH WRDWTYRDAV TPQERYSEEQ KAYFSTPPAQ RLALLGLAQP
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against MMACHC. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product MMACHC Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 282 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MMACHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC))
- Alternative Name
- MMACHC (MMACHC Products)
- Background
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The exact function of the protein encoded by this gene is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.
Alias Symbols: DKFZp564I122, FLJ25671, RP11-291L19.3, cblC
Protein Interaction Partner: MMADHC, UBC,
Protein Size: 282 - Molecular Weight
- 31 kDa
- Gene ID
- 25974
- NCBI Accession
- NM_015506, NP_056321
- UniProt
- Q9Y4U1
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