NDUFS8 antibody (C-Term)

Catalog No. ABIN2788918

Product Details anti-NDUFS8 Antibody

Target: NDUFS8 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 8, 23kDa (NADH-Coenzyme Q Reductase) (NDUFS8))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Zebrafish (Danio rerio), Guinea Pig, Goat, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDUFS8 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TKCIYCGFCQ EACPVDAIVE GPNFEFSTET HEELLYNKEK LLNNGDKWEA

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against NDUFS8. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 210 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NDUFS8

Target: NDUFS8 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 8, 23kDa (NADH-Coenzyme Q Reductase) (NDUFS8))

Alternative Name: NDUFS8 (NDUFS8 Products)

Synonyms: CI-23k antibody, CI23KD antibody, TYKY antibody, BC021616 antibody, CI-23kD antibody, ndufs8 antibody, wu:fb30b07 antibody, zgc:65835 antibody, zgc:77840 antibody, MGC85457 antibody, ND23 antibody, GB17476 antibody, DDBDRAFT_0169117 antibody, DDBDRAFT_0233205 antibody, DDB_0169117 antibody, DDB_0233205 antibody, zgc:109991 antibody, NADH:ubiquinone oxidoreductase core subunit S8 antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 8 antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 8a antibody, NADH:ubiquinone oxidoreductase core subunit S8 L homeolog antibody, NADH-quinone oxidoreductase subunit I antibody, NADH dehydrogenase Fe-S protein 8 antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 8b antibody, NDUFS8 antibody, Ndufs8 antibody, ndufs8a antibody, ndufs8.L antibody, ndufs8 antibody, LOC551078 antibody, ndufs8b antibody

Background: This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome.
Alias Symbols: CI23KD, TYKY, CI-23k
Protein Interaction Partner: MDM2, vpr, SURF1, SDHA, RPLP0, RAB5B, PSEN1, OPA1, NDUFV2, NDUFS6, NDUFV1, NDUFS3, NDUFS2, NDUFS1, MPV17, HSPA9, DHODH, CYC1, COX15, ABCC2, NDUFS7, RHOT2, NDUFAF3, SAMM50, UBC, GEM, ICT1,
Protein Size: 210

Molecular Weight: 23 kDa

Gene ID: 4728

NCBI Accession: NM_002496, NP_002487

UniProt: O00217