POLG2 antibody (N-Term)

Catalog No. ABIN2788963

Product Details anti-POLG2 Antibody

Target: POLG2 (Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLG2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KSHAELEGNG EHPEAPGSGE GSEALLEICQ RRHFLSGSKQ QLSRDSLLSG

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against POLG2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 485 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for POLG2

Target: POLG2 (Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2))

Alternative Name: POLG2 (POLG2 Products)

Synonyms: POLG2 antibody, im:7158733 antibody, si:ch211-157f15.3 antibody, HP55 antibody, MTPOLB antibody, PEOA4 antibody, POLB antibody, POLG-BETA antibody, POLGB antibody, mtpolb antibody, DNA polymerase gamma 2, accessory subunit antibody, polymerase (DNA directed), gamma 2, accessory subunit antibody, polymerase (DNA directed), gamma 2, accessory subunit L homeolog antibody, Polg2 antibody, POLG2 antibody, polg2 antibody, polg2.L antibody

Background: This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.
Alias Symbols: HP55, MTPOLB, PEOA4, POLB, POLG-BETA, POLGB
Protein Interaction Partner: PARP1, SUMO1,
Protein Size: 485

Molecular Weight: 53 kDa

Gene ID: 11232

NCBI Accession: NM_007215, NP_009146

UniProt: Q9UHN1