SARS2 antibody (N-Term)

Catalog No. ABIN2789218

Product Details anti-SARS2 Antibody

Target: SARS2 (seryl-tRNA Synthetase 2, Mitochondrial (SARS2))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SARS2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EEKAAVTEAV RALLANQDSG EVQQDPKYQG LRARGREIRK ELVHLYPREA

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SARS2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 518 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SARS2

Target: SARS2 (seryl-tRNA Synthetase 2, Mitochondrial (SARS2))

Alternative Name: SARS2 (SARS2 Products)

Synonyms: 2410015F05Rik antibody, D7Ertd353e antibody, SerRS antibody, SerRSmt antibody, SARS antibody, SARSM antibody, SERS antibody, SYS antibody, mtSerRS antibody, seryl-aminoacyl-tRNA synthetase 2 antibody, seryl-tRNA synthetase 2, mitochondrial antibody, Sars2 antibody, SARS2 antibody

Background: This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease.
Alias Symbols: FLJ20450, SARS, SARSM, SERS, SYS, SerRSmt, mtSerRS, SerRS
Protein Interaction Partner: ILF2, CDH2, CALU, PRKCDBP, NENF, MATR3, PPT2, TUFM, SPTAN1, MTHFD1, ILF3, CUL3, RAD21, UBC, ICT1, USP44, DMWD, CASP3, EEF1A1, PUF60,
Protein Size: 518

Molecular Weight: 57 kDa

Gene ID: 54938

NCBI Accession: NM_017827, NP_060297

UniProt: Q9NP81