MRPL1 antibody (N-Term)

Catalog No. ABIN2789275

Product Details anti-MRPL1 Antibody

Target: MRPL1 (Mitochondrial Ribosomal Protein L1 (MRPL1))

Binding Specificity: N-Term

Reactivity: Human, Rat, Dog, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KKTKKGAKEK TPDEKKDEIE KIKAYPYMEG EPEDDVYLKR LYPRQIYEVE

Predicted Reactivity: Dog: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against MRPL1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 303 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL1

Target: MRPL1 (Mitochondrial Ribosomal Protein L1 (MRPL1))

Alternative Name: MRPL1 (MRPL1 Products)

Synonyms: BM022 antibody, L1MT antibody, MRP-L1 antibody, 2410002L03Rik antibody, 5830418D04Rik antibody, AI462572 antibody, L1mt antibody, mitochondrial ribosomal protein L1 antibody, Mrpl1 antibody, MRPL1 antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family.
Alias Symbols: BM022, FLJ96680, L1MT, MRP-L1
Protein Interaction Partner: GOPC, UBC, SOX2, MRPL10, MMGT1, MRPL11, MRPS7, MRPL4, ACAD9, MSLN, TUFM, SDHA, MRPL12, ILF3, HSPA1L, DLAT, APP, CAND1, CUL3, ICT1,
Protein Size: 303

Molecular Weight: 33 kDa

Gene ID: 65008

NCBI Accession: NM_020236, NP_064621

UniProt: Q9BYD6