DRD3 antibody (C-Term)
-
- Target See all DRD3 Antibodies
- DRD3 (Dopamine Receptor D3 (DRD3))
-
Binding Specificity
- C-Term
-
Reactivity
- Human, Rat, Dog, Horse, Pig, Cow, Guinea Pig
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This DRD3 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- QERGGELKRE EKTRNSLMPL REKKATQMVA IVLGAFIVCW LPFFLTHVLN
- Predicted Reactivity
- Cow: 77%, Dog: 86%, Guinea Pig: 75%, Horse: 79%, Human: 100%, Pig: 79%, Rat: 86%
- Characteristics
- This is a rabbit polyclonal antibody against DRD3. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product DRD3 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 367 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- DRD3 (Dopamine Receptor D3 (DRD3))
- Alternative Name
- DRD3 (DRD3 Products)
- Synonyms
- DRD3 antibody, D3R antibody, D3DR antibody, ETM1 antibody, FET1 antibody, dopamine receptor D3 antibody, drd3 antibody, DRD3 antibody, Drd3 antibody
- Background
-
This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
Alias Symbols: D3DR, ETM1, FET1, MGC149204, MGC149205
Protein Interaction Partner: SLC9A3, USP48, EEF1G, CLIC6, MPDZ, EPB41L2, GIPC1, NCS1, EPB41L1, EEF1B2, NCK1, FLNA, GNAI1, EPB41, GRB2, RDX,
Protein Size: 367 - Molecular Weight
- 41 kDa
- Gene ID
- 1814
- NCBI Accession
- NM_033663, NP_387512
- UniProt
- P35462
- Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Negative Regulation of Transporter Activity
-