PINK1 antibody (N-Term)

Catalog No. ABIN2789443

Product Details anti-PINK1 Antibody

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Horse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PINK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: GCAGPCGRAV FLAFGLGLGL IEEKQAESRR AVSACQEIQA IFTQKSKPGP

Predicted Reactivity: Cow: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PINK1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 581 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PINK1

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Alternative Name: PINK1 (PINK1 Products)

Synonyms: BEST:GH23468 antibody, CG4523 antibody, Dmel\\CG4523 antibody, PINK antibody, PINK1 antibody, dPINK1 antibody, dPink1 antibody, pink1 antibody, wu:fc39e12 antibody, zgc:101729 antibody, BRPK antibody, PARK6 antibody, 1190006F07Rik antibody, AU042772 antibody, AW557854 antibody, mFLJ00387 antibody, PTEN-induced putative kinase 1 antibody, PTEN induced putative kinase 1 antibody, Pink1 antibody, PINK1 antibody, pink1 antibody

Background: This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease.
Alias Symbols: BRPK, FLJ27236, PARK6
Protein Interaction Partner: IMMT, RHOT2, MCL1, BCL2L2, BCL2L1, UBC, BAG2, CRLS1, FBXO7, SARM1, RB1CC1, TOMM20, VIM, TRAF6, HSPA1B, HSPA1A, PARK2, HSP90AA1, TOLLIP, MAP3K7, IRAK1, RICTOR, SENP8, MAPKAP1, COPS8, UBE2M, AKT1, NEDD8, PINK1, TOMM22, RHOT1, HTRA2, PARK7, CDC37, TOMM40, TO
Protein Size: 581

Molecular Weight: 63 kDa

Gene ID: 65018

NCBI Accession: NM_032409, NP_115785

UniProt: Q9BXM7

Pathways: Autophagy