PD-L1 antibody (C-Term)
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- Target See all PD-L1 Antibodies
- PD-L1 (CD274 (PD-L1))
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Binding Specificity
- C-Term
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Reactivity
- Human, Pig, Cow
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PD-L1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- NVTSTLRINT TTNEIFYCTF RRLDPEENHT AELVIPELPL AHPPNERTHL
- Predicted Reactivity
- Cow: 79%, Human: 100%, Pig: 100%
- Characteristics
- This is a rabbit polyclonal antibody against CD274. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product PD-L1 Primary Antibody
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anti-CD274 (PD-L1) (C-Term) antibody
Verified PD-L1 Reactivity: Human WB, FACS, ELISA, IF Host: Goat Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 19-238) antibodyPD-L1 Reactivity: Human WB, FACS, IHC, ELISA, IF Host: Mouse Monoclonal 9B5F4 unconjugated
anti-CD274 (PD-L1) (AA 24-153) antibodyPD-L1 Reactivity: Human WB, FACS, IHC, ELISA, ICC, Neut Host: Mouse Monoclonal 6D9A2 unconjugated
anti-CD274 (PD-L1) (AA 39-191) antibodyPD-L1 Reactivity: Human, Mouse WB, FACS, IHC, ELISA, IF, Coat, StM Host: Mouse Monoclonal PDL1-2746 unconjugated
anti-CD274 (PD-L1) (AA 48-290) antibodyPD-L1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 34-241) antibodyPD-L1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 24-153) antibodyPD-L1 Reactivity: Human WB, FACS, IHC, ELISA, ICC Host: Mouse Monoclonal 7D2A10 unconjugated
anti-CD274 (PD-L1) (C-Term) antibodyKO Validated PD-L1 Reactivity: Human WB, FACS, ICC, IF, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 19-238) antibodyPD-L1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-CD274 (PD-L1) antibodyKO Validated PD-L1 Reactivity: Human WB, IHC Host: Rabbit Monoclonal unconjugated
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 290 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PD-L1 (CD274 (PD-L1))
- Alternative Name
- CD274 (PD-L1 Products)
- Synonyms
- B7-H antibody, B7H1 antibody, PD-L1 antibody, PDCD1L1 antibody, PDCD1LG1 antibody, PDL1 antibody, A530045L16Rik antibody, B7h1 antibody, Pdcd1l1 antibody, Pdcd1lg1 antibody, Pdl1 antibody, RGD1566211 antibody, CD274 molecule antibody, CD274 antigen antibody, programmed cell death 1 ligand 2 antibody, CD274 antibody, Cd274 antibody, PDCD1LG2 antibody
- Background
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CD274 is involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
Alias Symbols: B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1, PDCD1LG1, PDL1
Protein Interaction Partner: PDCD1, CD80, PTPN11,
Protein Size: 290 - Molecular Weight
- 32 kDa
- Gene ID
- 29126
- NCBI Accession
- NM_014143, NP_054862
- UniProt
- Q9NZQ7
- Pathways
- Cancer Immune Checkpoints
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