FYB antibody (C-Term)
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- Target See all FYB Antibodies
- FYB (FYN-Binding Protein (FYB))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Dog, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FYB antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MGDEVYDDVD TSDFPVSSAE MSQGTNVGKA KTEEKDLKKL KKQEKEEKDF
- Predicted Reactivity
- Dog: 100%, Horse: 79%, Human: 100%, Mouse: 75%
- Characteristics
- This is a rabbit polyclonal antibody against FYB. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product FYB Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 829 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- FYB (FYN-Binding Protein (FYB))
- Alternative Name
- FYB (FYB Products)
- Synonyms
- fyb antibody, ADAP antibody, PRO0823 antibody, SLAP-130 antibody, B630013F22Rik antibody, FYB-120/130 antibody, Slap130 antibody, p120/130 antibody, p120/p130 antibody, RGD1563421 antibody, FYN-binding protein antibody, FYN binding protein 1 antibody, FYN binding protein antibody, fyb antibody, FYB1 antibody, Fyb antibody, Fyb1 antibody
- Background
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The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interleukin-2. Three transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ADAP, PRO0823, SLAP-130
Protein Interaction Partner: UBC, Mbp, LCP2, FYN, FASLG, CBL, CARD11, BCL10, MAP3K7, PRKCQ, ENAH, EVL, SKAP2, SKAP1, CBLB, BCAR1, VASP, SH2D1A, WAS, SRC,
Protein Size: 829 - Molecular Weight
- 96 kDa
- Gene ID
- 2533
- NCBI Accession
- NM_199335, NP_955367
- UniProt
- E9PBV9
- Pathways
- TCR Signaling, Protein targeting to Nucleus
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