FCGR2B antibody (C-Term)

Catalog No. ABIN2789535

Product Details anti-FCGR2B Antibody

Target: FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FCGR2B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VALIYCRKKR ISANPTNPDE ADKVGAENTI TYSLLMHPDA LEEPDDQNRI

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against FCGR2B. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 290 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FCGR2B

Target: FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))

Alternative Name: FCGR2B (FCGR2B Products)

Synonyms: CD32 antibody, CD32B antibody, FCG2 antibody, FCGR2 antibody, IGFR2 antibody, FCGR2B antibody, AI528646 antibody, F630109E10Rik antibody, Fc[g]RII antibody, FcgRII antibody, Fcgr2 antibody, Fcgr2a antibody, Fcr-2 antibody, Fcr-3 antibody, Ly-17 antibody, Ly-m20 antibody, LyM-1 antibody, Lym-1 antibody, FCRII antibody, FcRII antibody, Fc fragment of IgG receptor IIb antibody, Fc fragment of IgG, low affinity IIb, receptor (CD32) antibody, Fc receptor, IgG, low affinity IIb antibody, low affinity immunoglobulin gamma Fc region receptor II antibody, FCGR2B antibody, Fcgr2b antibody, LOC100856270 antibody

Background: The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD32, CD32B, FCG2, FCGR2, IGFR2
Protein Interaction Partner: INPP5D, C14orf1, MAPK3, LY6E, INPPL1, BLK, MAPK1, PTPN6, LYN, CRP, APCS, SHC1, PTPN11,
Protein Size: 290

Molecular Weight: 32 kDa

Gene ID: 2213

NCBI Accession: NM_001002273, NP_001002273

UniProt: P31994

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, BCR Signaling