GHSR antibody (C-Term)

Catalog No. ABIN2789563

Product Details anti-GHSR Antibody

Target: GHSR (Growth Hormone Secretagogue Receptor (GHSR))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GHSR antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AAINPILYNI MSKKYRVAVF RLLGFEPFSQ RKLSTLKDES SRAWTESSIN

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against GHSR. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 366 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GHSR

Target: GHSR (Growth Hormone Secretagogue Receptor (GHSR))

Alternative Name: GHSR (GHSR Products)

Synonyms: GHSR antibody, C530020I22Rik antibody, growth hormone secretagogue receptor antibody, growth hormone secretagogue receptor,putative antibody, GHSR antibody, Smp_164730 antibody, Ghsr antibody

Background: This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein, this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin, however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.
Alias Symbols: -
Protein Interaction Partner: GHRL, CORT,
Protein Size: 366

Molecular Weight: 40 kDa

Gene ID: 2693

NCBI Accession: NM_198407, NP_940799

UniProt: B3SXS8

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Feeding Behaviour