TNFRSF13C antibody (C-Term)
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- Target See all TNFRSF13C Antibodies
- TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TNFRSF13C antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PGISDATAPA WPPPGEDPGT TPPGHSVPVP ATELGSTELV TTKTAGPEQQ
- Predicted Reactivity
- Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against TNFRSF13C. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product TNFRSF13C Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 184 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
- Alternative Name
- TNFRSF13C (TNFRSF13C Products)
- Synonyms
- RGD1560810 antibody, TNFRSF13C antibody, BAFF-R antibody, BAFFR antibody, BROMIX antibody, CD268 antibody, CVID4 antibody, prolixin antibody, 2010006P15Rik antibody, Baffr antibody, Bcmd antibody, Bcmd-1 antibody, Bcmd1 antibody, Lvis22 antibody, TNF receptor superfamily member 13C antibody, uncharacterized LOC746611 antibody, tumor necrosis factor receptor superfamily, member 13c antibody, TNFRSF13C antibody, Tnfrsf13c antibody, LOC746611 antibody
- Background
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B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
Alias Symbols: BAFF-R, BAFFR, CD268, MGC138235, CVID4, BROMIX, prolixin
Protein Interaction Partner: TNFSF13B, TRAF3IP2, TRAF3, TRAF2, TRAF1, TNFRSF13C,
Protein Size: 184 - Molecular Weight
- 20 kDa
- Gene ID
- 115650
- NCBI Accession
- NM_052945, NP_443177
- UniProt
- Q96RJ3
- Pathways
- NF-kappaB Signaling
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