THEMIS antibody (C-Term)

Catalog No. ABIN2789620

Product Details anti-THEMIS Antibody

Target: THEMIS (Thymocyte Selection Associated (THEMIS))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THEMIS antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RHHVDITKKL HPNQAGLDSK VLIGSQNDLV DEEKERSNRG ATAIAETFKN

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against THEMIS. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 606 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for THEMIS

Target: THEMIS (Thymocyte Selection Associated (THEMIS))

Alternative Name: THEMIS (THEMIS Products)

Synonyms: TSEPA antibody, C6orf190 antibody, C6orf207 antibody, GASP antibody, SPOT antibody, bA325O24.3 antibody, bA325O24.4 antibody, A430108D01 antibody, BB160712 antibody, E430004N04Rik antibody, Gasp antibody, Tsepa antibody, thylex antibody, C9H6ORF190 antibody, im:7138580 antibody, tsepa antibody, thymocyte selection associated antibody, THEMIS antibody, Themis antibody, themis antibody

Background: THEMIS plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. It is required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. It regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.
Alias Symbols: C6orf190, C6orf207, FLJ40584, MGC163388, TSEPA, bA325O24.3, bA325O24.4, GASP, SPOT
Protein Interaction Partner: UBC, PRMT6,
Protein Size: 606

Molecular Weight: 66 kDa

Gene ID: 387357

NCBI Accession: NM_001164687, NP_001158159

UniProt: Q8N1K5