CASQ2 antibody (N-Term)

Catalog No. ABIN2789644

Product Details anti-CASQ2 Antibody

Target: CASQ2 (Calsequestrin 2 (CASQ2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASQ2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DRVVSLSEKN FKQVLKKYDL LCLYYHEPVS SDKVTQKQFQ LKEIVLELVA

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CASQ2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 399 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CASQ2

Target: CASQ2 (Calsequestrin 2 (CASQ2))

Alternative Name: CASQ2 (CASQ2 Products)

Synonyms: CASQ2 antibody, DKFZp468D075 antibody, AA033488 antibody, AW146219 antibody, ESTM52 antibody, cCSQ antibody, PDIB2 antibody, cardCSQ antibody, CASQ1 antibody, CAL antibody, calsequestrin 2 antibody, CASQ2 antibody, Casq2 antibody

Background: The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.
Alias Symbols: FLJ26321, FLJ93514, PDIB2
Protein Interaction Partner: ANKRD1, TRDN, CSNK2A2, CSNK2A1,
Protein Size: 399

Molecular Weight: 46 kDa

Gene ID: 845

NCBI Accession: NM_001232, NP_001223

UniProt: O14958

Pathways: Negative Regulation of Transporter Activity